NORTHEAST MASS CYTOMETRY JOURNAL CLUB

Enjoy this discussion led by Caroline Roe, MLI, Managing Director of the Mass Cytometry Center of Excellence and the Cancer Immunology Core at Vanderbilt University Medical Center, a CYTO SRL Emerging Leader, and an active journal club member! Caroline discusses how her core at Vanderbilt helps researchers employ mass cytometry in support of clinical trials, the novel algorithm Trex developed by Vanderbilt researchers, and her general thoughts on CyTOF.

Our February 2022 Journal Club featuring guest was Dr. Lior Goldberg, City of Hope, who presented his work studying the immune signatures of CAR T cells. Dr. Goldberg's work featured mass cytometry as the tool of choice for immune-profiling 6 timepoints across multiple patients, leading to novel findings on the spatiotemporal plasticity in CAR T cells. #CyTOF #CAR T Cells

From 2021's first Northeast Mass Cytometry Journal Club: Olink's Daniel Frederick, PhD and Fluidigm's Andrew Draghi, PhD discuss the benefits of multi-OMIQs analysis, in the context of Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans by Arunachalam & Wimmers et al 2020. About the Northeast Mass Cytometry Journal Club: The NEMCJC is an active community of scientists and researchers from both academia and biopharma institutions that strives to foster engagement, discussion, and critique of cutting edge research, especially in topics relevant to mass cytometry, in order to build a community of collaboration, progress, and reflection. The hope for NEMCJC is that it provides a place for members to thoughfully engage in scientific discourse and debate, while building relationships with colleagues from across industries. The NEMCJC is sponsored by Ionic Cytometry Solutions. For more information on joining the club or about the services Ionic Cytometry provides, please visit our website: https://www.ioniccytometry.com/ !

In this month's installment of the Northeast Mass Cytometry Journal Club, Dmitry Bandura, co-inventor of the CyTOF technology and co-founder of DVS Sciences/Fluidigm Canada, joins us to give a little more insight into CyTOF technology. Eric Haas, of Ionic Cytometry Solutions, leads this webinar reviewing some of the fundamental components of how mass cytometry works, as described in the seminal paper, Mass Cytometry: Technique for Real Time Single Cell Multitarget Immunoassay Based on Inductively Coupled Plasma Time-of-Flight Mass Spectrometry by Bandura et al., 2009. If interested in joining these discussions, please visit ioniccytometry.com for more information.

To kick off the 2022 NEMC Journal Club season, we are joined by Dr. Ben Spurgeon to learn more about Platelet CyTOF. In this lecture and discussion, Ben dives into the optimization that he performed in order to use CyTOF (Mass Cytometry) for the study of platelet heterogeneity. This presentation was sponsored by Ionic Cytometry Solutions. For more information on the mass and flow cytometry services ICS provides, check out our website today! ioniccytometry.com